Sigma Alpha Epsilon at the University of South Dakota encourages members to branch out and explore the wonderful opportunities provided by extracuricular activities and organizations. Below is a list of several of the areas the chapter is involved with:

Coyote Capital Management
Students in Free Enterprise
Student Government Association
Dance Marathon
Hope 4 Africa
Honors Program
Tech Fellow
Pre Optometry Club
Honors Program-Psychology Majors
Contemporary Media and Journalism
Lost and Found
Pre Med Society
Criminal Justice
Business Management
Student Ambassadors
College Libertarians
Club Baseball
Coaches Vs Cancer
College Democrats
Political Science League
Hockey and Tennis Club
College Republicans
The One Percent
Coyote Crew
Health Service Admin
Pre Dental Club
Chamber Singers
Business Administration